Some people are gluten-intolerant, meaning that their bodies find it difficult to break down during digestion, it is very rare for someone to actually be allergic to wheat which would generally cause skin, respiratory and / or gastrointestinal reactions to wheat allergens. The most common wheat intolerance is celiac disease, when someone with celiac disease eats gluten it triggers an immune response that damages his or her intestines. A lot of people feel that they have a sensitivity to gluten and choose not to eat it or to limit their consumption of it in their day-to-day diet.